Pantothenic Acid - Fatty Liver Help
The effects of pantethine on fatty liver and fat distribution.Osono Y, Hirose N, Nakajima K, Hata Y.SourceHealth Administration Center, Aoyama Gakuin University, Tokyo, Japan.
AbstractAlthough the prognosis of fatty liver depends on its causes, we feel from our clinical experience that fatty liver with hypertriglyceridemia has a good prognosis and responds well to treatment. In this study, 600 mg/day of pantethine was administered to 16 outpatients with fatty liver and hypertriglyceridemia for six months or longer to examine whether the drug improved fatty liver using abdominal plain computed tomography (CT). Nine of the 16-pantethine patients were no longer diagnosed as having fatty liver after the study period. An chi2 test indicated the significant disappearance of fatty liver. At the same time, the visceral fat calculated from the CT image passing the umbilical region was also significantly reduced. On the contrary, the subcutaneous fat area tended to increase, so the ratio of the visceral-to-subcutaneous fat area was reduced significantly. This indicates triglycerides may be pooled in the body as hepato-visceral fat and subcutaneous fat, and that pantethine may transfer fat from the liver and viscera to the subcutaneous tissue. This suggests that visceral fat deposition and fatty liver occurring with hypertriglyceridemia may have a common basis, probably excessive matrixes, and that pantethine may simultaneously improve the two conditions
Liver and Gallbladder Cleansing Instructions
The Liver flush requires six days of preparation, followed by 16-20 hours of actual cleansing. To remove cholesterol, you need the following items:
Choose ORGANIC Products when available:
Apple Juice Six 1-liter (32 oz) containers
Epson Salt 4 tablespoons dissolved in three 8 oz. glasses of water.
Virgin olive oil, cold-pressed One-half glass (4 oz)
Either fresh grapefruit (pink is best), or fresh lemon and orange combined*Enough to squeeze 2/3 glass of juice; 2 pint jars, one with a lid.
*If you cannot tolerate grapefruit juice or if it tends to make you nauseous, you may use equal amounts of freshly squeezed lemon and orange juice instead. The effect is the same with either choice.
1. Drink 1 liter (32 oz.) of apple juice per day for a period of six days minimum. The malic acid in the apple juice softens the gallstones and makes their passage through the bile ducts smooth and easy. The apple juice has a strong cleansing effect. Drink the apple juice slowly throughout the day, between meals (avoid drinking the juice during, just before and in the first two hours after meal, and in the evening). This is in addition to your normal water intake.
2. Dietary recommendations: During the entire week of preparation and cleansing, avoid taking foods or beverages that are cold or chilled; they chill the liver and, thereby, reduce the effectiveness of the cleanse. All foods or beverages should be warm or at least room temperature. To help the liver prepare for the main flush, do not eat animal products, dairy products and fried food items. Otherwise, eat normal meals, but avoid overeating.
3. The best times for cleansing: The main and final part of the liver flush is best done over a weekend when you are not under any pressure and have enough time to rest. Although the cleanse is effective at any time of the month, it should preferably coincide with a day between full moon and new moon. Try to avoid doing the actual flush on the full moon itself. The day of new moon is the most conducive for cleansing and healing.
4. If you take any medication: While on the liver flush regimen, avoid taking any medication, vitamins or supplements that are not absolutely necessary, it is important not to give the liver any extra work that could interfere with its cleansing efforts.
5. Make sure that you cleanse your colon before and after you do a liver flush. Colon cleansing, either done a few days before or, ideally, on the sixth day of preparation, helps to avoid or minimize any discomfort or nausea that may arise during the actual liver flush. It prevents back-flushing of the oil mixture or waste products from the intestinal tract. It also assists the body in swiftly eliminating the gallstones.
6. What you need to do on the sixth day of drinking apple juice: If you feel hungry in the morning, eat a light breakfast, such as a hot cereal; oatmeal would be an ideal choice. Avoid sugar or other sweeteners, spices, milk butter, oils, yogurt, cheese, ham, eggs, nuts, pastries, cold cereals, etc. Fruits or vegetables with white rice (preferably Basmati rice) and flavor it with a little unrefined sea or rock salt. To repeat, do not eat any protein foods, butter or oil, or you might feel ill during the actual cleanse. Do not eat or drink anything (except water) after 2 PM, otherwise, you may not flush out any stones! Follow the exact timing given below to receive the maximum benefit from the liver flush.
Evening
6:00 PM: Add four tablespoons of Epson Salt to a total of 24 ounces (three 8 oz. glasses) of filtered water in a jar. This makes four 6 oz. servings. Drink your first portion (3/4 glass) now. You may take a few sips of water afterwards to neutralize the bitter taste in the mouth or add a little lemon juice to improve the taste. Some people drink it with a large plastic straw to bypass the taste buds on the tongue. It is also helpful to rinse out the mouth with baking soda. One of the main actions of the Epson Salt is to dilate (widen) the bile ducts, making it easy for the stones to pass. Moreover, it clears out waste that may obstruct the release of the stones.
8:00 PM: Drink your second serving (3/4 glass) of Epson Salt.
9:30 PM: If you have not had a bowel movement until now and not done a colon cleanse within the past 24 hours, take a water enema; this will trigger a series of bowel movements.
9:45 PM: Thoroughly wash the grapefruits (or lemons and oranges). Squeeze them by hand and remove pulp. You will need ¾ glass of juice. Pour the juice and ½ glass of olive oil into the pint jar. Close the jar tightly and shake hard, about 20 times or until the solution is watery. Ideally, you should drink this mixture at 10:00 PM, but if you feel you still need to visit the bathroom a few more times, you may delay this step for up to 10 minutes.
10:00 PM: Stand next to your bed (do not sit down) and drink the concoction, if possible, straight. Do not take more than 5 minutes for this.
Lie on your right side with your knees pulled towards your head. Lie perfectly still for a least 20 minutes and try not to speak! Put your attention on your liver. There won't be any spasms or pain because the Epson Salt keeps the bile duct valves wide open and relaxed, and the bile that is excreted along with the stones keeps the bile ducts well lubricated. Go to sleep if you can.
The Following Morning
6:00-6:30 AM: Upon awakening, but not before 6 AM, drink your third ¾ glass of Epson Salt. Rest, read or meditate. If you are very sleepy, you may go back to bed, although it is best if the body stays in the upright position. Most people feel fine and prefer to do some light exercises, such as
Yoga.
8:00-8:30 AM: Drink your fourth and last ¾ glass of Epson Salt.
10:00-10:30 AM: You may drink freshly pressed fruit juice at this time. One half-hour later, you may eat one or two pieces of fresh fruit. One hour later, you may eat regular (but lightly) food. By the evening or the next morning, you should be back to normal, and feel the first signs of improvement.
Continue to eat light meals during the following days. Remember, your liver and gallbladder underwent major "surgery", albeit without harmful side effects.
Note: Drink water whenever thirsty, except right after drinking Epson Salt and for the first two hours after drinking the oil mixture.
The Liver flush requires six days of preparation, followed by 16-20 hours of actual cleansing. To remove cholesterol, you need the following items:
Choose ORGANIC Products when available:
Apple Juice Six 1-liter (32 oz) containers
Epson Salt 4 tablespoons dissolved in three 8 oz. glasses of water.
Virgin olive oil, cold-pressed One-half glass (4 oz)
Either fresh grapefruit (pink is best), or fresh lemon and orange combined*Enough to squeeze 2/3 glass of juice; 2 pint jars, one with a lid.
*If you cannot tolerate grapefruit juice or if it tends to make you nauseous, you may use equal amounts of freshly squeezed lemon and orange juice instead. The effect is the same with either choice.
1. Drink 1 liter (32 oz.) of apple juice per day for a period of six days minimum. The malic acid in the apple juice softens the gallstones and makes their passage through the bile ducts smooth and easy. The apple juice has a strong cleansing effect. Drink the apple juice slowly throughout the day, between meals (avoid drinking the juice during, just before and in the first two hours after meal, and in the evening). This is in addition to your normal water intake.
2. Dietary recommendations: During the entire week of preparation and cleansing, avoid taking foods or beverages that are cold or chilled; they chill the liver and, thereby, reduce the effectiveness of the cleanse. All foods or beverages should be warm or at least room temperature. To help the liver prepare for the main flush, do not eat animal products, dairy products and fried food items. Otherwise, eat normal meals, but avoid overeating.
3. The best times for cleansing: The main and final part of the liver flush is best done over a weekend when you are not under any pressure and have enough time to rest. Although the cleanse is effective at any time of the month, it should preferably coincide with a day between full moon and new moon. Try to avoid doing the actual flush on the full moon itself. The day of new moon is the most conducive for cleansing and healing.
4. If you take any medication: While on the liver flush regimen, avoid taking any medication, vitamins or supplements that are not absolutely necessary, it is important not to give the liver any extra work that could interfere with its cleansing efforts.
5. Make sure that you cleanse your colon before and after you do a liver flush. Colon cleansing, either done a few days before or, ideally, on the sixth day of preparation, helps to avoid or minimize any discomfort or nausea that may arise during the actual liver flush. It prevents back-flushing of the oil mixture or waste products from the intestinal tract. It also assists the body in swiftly eliminating the gallstones.
6. What you need to do on the sixth day of drinking apple juice: If you feel hungry in the morning, eat a light breakfast, such as a hot cereal; oatmeal would be an ideal choice. Avoid sugar or other sweeteners, spices, milk butter, oils, yogurt, cheese, ham, eggs, nuts, pastries, cold cereals, etc. Fruits or vegetables with white rice (preferably Basmati rice) and flavor it with a little unrefined sea or rock salt. To repeat, do not eat any protein foods, butter or oil, or you might feel ill during the actual cleanse. Do not eat or drink anything (except water) after 2 PM, otherwise, you may not flush out any stones! Follow the exact timing given below to receive the maximum benefit from the liver flush.
Evening
6:00 PM: Add four tablespoons of Epson Salt to a total of 24 ounces (three 8 oz. glasses) of filtered water in a jar. This makes four 6 oz. servings. Drink your first portion (3/4 glass) now. You may take a few sips of water afterwards to neutralize the bitter taste in the mouth or add a little lemon juice to improve the taste. Some people drink it with a large plastic straw to bypass the taste buds on the tongue. It is also helpful to rinse out the mouth with baking soda. One of the main actions of the Epson Salt is to dilate (widen) the bile ducts, making it easy for the stones to pass. Moreover, it clears out waste that may obstruct the release of the stones.
8:00 PM: Drink your second serving (3/4 glass) of Epson Salt.
9:30 PM: If you have not had a bowel movement until now and not done a colon cleanse within the past 24 hours, take a water enema; this will trigger a series of bowel movements.
9:45 PM: Thoroughly wash the grapefruits (or lemons and oranges). Squeeze them by hand and remove pulp. You will need ¾ glass of juice. Pour the juice and ½ glass of olive oil into the pint jar. Close the jar tightly and shake hard, about 20 times or until the solution is watery. Ideally, you should drink this mixture at 10:00 PM, but if you feel you still need to visit the bathroom a few more times, you may delay this step for up to 10 minutes.
10:00 PM: Stand next to your bed (do not sit down) and drink the concoction, if possible, straight. Do not take more than 5 minutes for this.
Lie on your right side with your knees pulled towards your head. Lie perfectly still for a least 20 minutes and try not to speak! Put your attention on your liver. There won't be any spasms or pain because the Epson Salt keeps the bile duct valves wide open and relaxed, and the bile that is excreted along with the stones keeps the bile ducts well lubricated. Go to sleep if you can.
The Following Morning
6:00-6:30 AM: Upon awakening, but not before 6 AM, drink your third ¾ glass of Epson Salt. Rest, read or meditate. If you are very sleepy, you may go back to bed, although it is best if the body stays in the upright position. Most people feel fine and prefer to do some light exercises, such as
Yoga.
8:00-8:30 AM: Drink your fourth and last ¾ glass of Epson Salt.
10:00-10:30 AM: You may drink freshly pressed fruit juice at this time. One half-hour later, you may eat one or two pieces of fresh fruit. One hour later, you may eat regular (but lightly) food. By the evening or the next morning, you should be back to normal, and feel the first signs of improvement.
Continue to eat light meals during the following days. Remember, your liver and gallbladder underwent major "surgery", albeit without harmful side effects.
Note: Drink water whenever thirsty, except right after drinking Epson Salt and for the first two hours after drinking the oil mixture.
Pantothenic Acid, also known as vitamin B5, is one of eight vitamins that comprise the B complex. Pantothenic acid is part of coenzyme A (CoA), an essential metabolite the body uses to produce energy from food (fats, carbohydrates and proteins).
Since pantothenic acid is found in a wide variety of foods, deficiencies are rare. The symptoms of experimental deficiency include headache, fatigue, gastrointestinal diistress, insomnia, weakness and impaired motor coordination.
Food sources include poultry, fish, meat, broccoli, egg yolk, mushrooms, and legumes. Whole grains are also good sources of pantothenic acid, but a significant amount is lost during refining and processing. Cooking, freezing and canning can also destroy some of the pantothenic acid available in foods.
While no RDA (recommended daily allowance) exists for pantothenic acid, the amount considered adequate in adult diets is 4 to 7 mg. This is consistent with the average intake of 2mg–3mg/1000 calories in typical diets.
Supplements of pantothenic acid are usually taken in much higher amounts. Vitamin B supplements and other nutrient preparations may contain 100mg–500mg of pantothenic acid per serving. Although this is many times the amount considered adequate for general health, there appears to be no danger from taking large, supplemental doses.
This is a good thing, too, since megadoses (1g–10g per day) of pantothenic acid are frequently recommended to treat acne, adrenal fatigue, stress, migraines and sinus conditions.
Most of these uses are speculative, and based on little—if any—reliable research.
This doesn't mean "wrong", of course, but it does mean that positive claims are largely anecdotal, and need to be taken with a grain of salt.
Several forms of pantothenic acid have documented uses, however.
One is pantethine, which is a compound containing two molecules of pantothenic acid linked by a sulfur "bridge". Pantethine has been shown to improve fatty liver and high triglycerides, as well as cholesterol levels in small, human clinical studies.
Panthenol is another useful derivative. It's typically used topically in moisturizing cosmetic products for hair and skin. Dexpanthenol (the purified "D" isomer of panthenol) is also used in commercial hair loss treatments, as well as in medical products for wound healing/repair.
In Europe, it's also used in certain over-the-counter nasal sprays, as research has shown dexpanthenol may help reduce nasal irritation/congestion from allergies or surgery.
Like all B vitamins, pantothenic acid is water-soluble, which is why it's difficult to overdose on it. The body excretes excess amounts of vitamin B5 naturally, though extremely high doses (10g–20g) may cause diarrhea. Likewise, pantethine is generally well-tolerated in doses up to 1,200mg/day, although some gastrointestinal side-effects (nausea and heartburn) have been reported.
Since pantothenic acid is found in a wide variety of foods, deficiencies are rare. The symptoms of experimental deficiency include headache, fatigue, gastrointestinal diistress, insomnia, weakness and impaired motor coordination.
Food sources include poultry, fish, meat, broccoli, egg yolk, mushrooms, and legumes. Whole grains are also good sources of pantothenic acid, but a significant amount is lost during refining and processing. Cooking, freezing and canning can also destroy some of the pantothenic acid available in foods.
While no RDA (recommended daily allowance) exists for pantothenic acid, the amount considered adequate in adult diets is 4 to 7 mg. This is consistent with the average intake of 2mg–3mg/1000 calories in typical diets.
Supplements of pantothenic acid are usually taken in much higher amounts. Vitamin B supplements and other nutrient preparations may contain 100mg–500mg of pantothenic acid per serving. Although this is many times the amount considered adequate for general health, there appears to be no danger from taking large, supplemental doses.
This is a good thing, too, since megadoses (1g–10g per day) of pantothenic acid are frequently recommended to treat acne, adrenal fatigue, stress, migraines and sinus conditions.
Most of these uses are speculative, and based on little—if any—reliable research.
This doesn't mean "wrong", of course, but it does mean that positive claims are largely anecdotal, and need to be taken with a grain of salt.
Several forms of pantothenic acid have documented uses, however.
One is pantethine, which is a compound containing two molecules of pantothenic acid linked by a sulfur "bridge". Pantethine has been shown to improve fatty liver and high triglycerides, as well as cholesterol levels in small, human clinical studies.
Panthenol is another useful derivative. It's typically used topically in moisturizing cosmetic products for hair and skin. Dexpanthenol (the purified "D" isomer of panthenol) is also used in commercial hair loss treatments, as well as in medical products for wound healing/repair.
In Europe, it's also used in certain over-the-counter nasal sprays, as research has shown dexpanthenol may help reduce nasal irritation/congestion from allergies or surgery.
Like all B vitamins, pantothenic acid is water-soluble, which is why it's difficult to overdose on it. The body excretes excess amounts of vitamin B5 naturally, though extremely high doses (10g–20g) may cause diarrhea. Likewise, pantethine is generally well-tolerated in doses up to 1,200mg/day, although some gastrointestinal side-effects (nausea and heartburn) have been reported.